Ecto-Phosphorylation of CD98 Regulates Cell-Cell Interactions

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Ecto-Phosphorylation of CD98 Regulates Cell-Cell Interactions

Ecto-phosphorylation plays an important role in many cellular functions. The transmembrane glycoprotein CD98 contains potential phosphorylation sites in its extracellular C-terminal tail. We hypothesized that extracellular signaling through ecto-protein kinases (ePKs) might lead to ecto-phosphorylation of CD98 and influence its multiple functions, including its role in cell-cell interactions. O...

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ژورنال

عنوان ژورنال: PLoS ONE

سال: 2008

ISSN: 1932-6203

DOI: 10.1371/journal.pone.0003895